Paracetamol - London Pain Clinic (2024)

Introduction

Paracetamol is one of the most common analgesic and antipyretic drugs used in pain management. The fact that paracetamol does not irritate the stomach makes it the most popular painkiller in use.

Research indicates that paracetamol works by blocking the production of chemicals, known as prostaglandins, which are involved in pain transmission.

Paracetamol is one of the most common drugs used in the world and is manufactured in huge quantities. The drug is commonly marketed under a vast range of brand names. Here we list a few main amongst them:

Algina

Alice

Oxymark

Calpol

Cemol

Cofamol

Crocin Dispirin

Fevastin

Genmole

Ifimol

Larkin

Common Uses

Paracetamol is generally prescribed for relief from mild to moderate pain. The most common medical conditions for which paracetamol is recommended include:

Fever

Tension headache

Migraine headache

Muscular aches

Neuralgia

Backache

Joint pain

Rheumatic pain

Toothache

Teething pain

Period pain

Minor aches and pains

Muscle and joint pain

Post-immunization pyrexia (high temperature after immunization)

Also known as, acetaminophen, paracetamol is a major ingredient in numerous cold and flu medications, as well as many prescription analgesics. When combined with decongestant ingredients, paracetamol is highly effective in relieving the symptoms of common cold, influenza and sinusitis.

Things to consider

There are a few basic facts that must be remembered while on a prescription of paracetamol. Here we list the main points that are important:

Overdose of paracetamol is dangerous and capable of causing serious damage to the liver and kidneys.

Alcohol increases the risk of liver damage that can occur if an overdose of paracetamol is taken.

Consult your doctor if symptoms exist for more than three days.

Patients with a decreased kidney and liver function should use paracetamol with caution

Dosages required

Paracetamol is available in tablets, syrups, drops and suspension. The recommended dosage for adults is 500 mg to 1000 mg every 4-6 hours, up to a maximum of 4000 mg (8 tablets) in 24 hours.

For children, the doses for paracetamol depend on the age and weight. Though it can be given to young babies after vaccinations on doctor’s advice, it is generally not recommended for babies under three months of age.

Syrups containing paracetamol, such as Calpol, are easier to be taken for younger children. In fact, paracetamol is the most common over-the-counter medication prescribed for children.

Side effects

When taken at the prescribed dosage, there are almost no side effects of paracetamol.

However, there are certain limited side effects of paracetamol in some cases. These include:

Nausea

Stomach ache

Epigastric distress

Skin rash

Swelling of pancreas after prolonged use

Links for Medication

Paracetamol - London Pain Clinic (2024)

FAQs

How effective is paracetamol for pain relief? ›

For postoperative pain, perhaps one in four people benefit; for headache perhaps one in ten. This evidence comes from systematic reviews, often of large numbers of good clinical trials. These are robust and trustworthy results.

How strong is paracetamol for pain? ›

Paracetamol is a medicine used for mild to moderate pain. It can be bought over the counter in pharmacies, supermarkets and other shops. You can also take paracetamol for: fever (high temperature)

What is in paracetamol that stops pain? ›

Paracetamol seems to work by blocking the chemical messengers in the brain that tell your body that you have pain. It also reduces a high temperature by affecting the chemical messengers in an area of the brain that regulates body temperature.

What is the strongest drug for nerve pain? ›

Anticonvulsants are one of the most effective medications for treating nerve pain. Examples include pregabalin (Lyrica) and gabapentin (Neurontin). These medications are typically very effective in treating nerve pain, but they may also cause undesired side effects, such as: lethargy.

Is 500mg paracetamol enough for pain? ›

Paracetamol is a good general pain management medication. It is used to help manage lots of different types of chronic pain. The usual dose for paracetamol is 1-2 tablets (500-1000mg) four times a day.

Which is better for pain Tylenol or paracetamol? ›

Acetaminophen (Tylenol) and paracetamol (Panadol) are the same pain-relieving medication. In the U.S. and Japan, it is called acetaminophen and paracetamol in Europe and most of the rest of the world. Acetaminophen (Tylenol) and paracetamol (Panadol) are the same medication. Both drugs are chemically the same: C8H9NO2.

Does paracetamol help nerve pain? ›

Relieving nerve pain. You may also require medicine to treat any nerve pain (neuropathic pain) you're experiencing. Unlike most other types of pain, neuropathic pain does not usually get better with common painkillers, such as paracetamol and ibuprofen, and other medicines are often used.

Can paracetamol use in chronic pain? ›

Painkillers for long-term pain

Paracetamol for adults is the simplest and safest painkiller. You could also try anti-inflammatory tablets like ibuprofen for adults as long as you don't have a condition (such as a stomach ulcer) that prevents you using them.

What is the brand name for paracetamol for pain? ›

Other names
Generic nameBrand names
ParacetamolDymadon®, Lemsip®, Panadol®, Panamax®, Tylenol®
Paracetamol and codeinePanadeine Forte®, Panamax Co®
Paracetamol, codeine and doxylamineMersyndol® and Mersyndol Forte®, Panalgesic®
Dec 7, 2023

What stops nerve pain immediately? ›

Painkillers. For severe nerve pain, powerful opioid painkillers can help. Studies have found that for many types of nerve pain, they are as effective as anticonvulsants or antidepressants. Unlike other treatments for nerve pain, they also work very quickly.

What is the safest pain reliever for seniors? ›

Acetaminophen (Tylenol) is usually safer for older adults than other pain medicines. Topical pain medicines (also called topical analgesics) can also help. When common pain medicines don't work to manage pain, your healthcare provider may suggest other medicines, such as antidepressants or anticonvulsants.

What is the best medication for severe chronic pain? ›

Serotonin and norepinephrine reuptake inhibitors, known as SNRIs , that may be prescribed to relieve chronic pain include duloxetine (Cymbalta, Drizalma Sprinkle), venlafaxine (Effexor XR, Pristiq) and milnacipran (Fetzima, Savella).

Is paracetamol a better painkiller than ibuprofen? ›

This means that ibuprofen may be more effective in reducing pain associated with inflammation, such as joint and muscle pain. On the other hand, paracetamol is typically better at reducing pain and fever that are not primarily caused by inflammation.

Which is the stronger painkiller paracetamol or ibuprofen? ›

While it used to be believed that ibuprofen shouldn't be given to young children, a 2020 review of 19 studies found that ibuprofen was more effective than paracetamol at controlling fever and pain in children under two, and it had very low rates of adverse reactions.

Is ibuprofen stronger than paracetamol? ›

Is ibuprofen a “stronger” medicine than paracetamol? Ibuprofen and paracetamol are equally strong for treatment of pain and fever. Ibuprofen has more anti-inflammatory effect (e.g., reducing redness and swelling). This is why it is often used to treat joint and muscle pain in adults.

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