About Topinate Gel 30 gm
Topinate Gel 30 gm belongs to a class of topical corticosteroid medications. It is used for the treatment of autoimmune skin disorders such as psoriasis (scaly, itchy, and red patches on the skin), lichen planus (purplish, itchy, and flat bumps on the wrists, forearms, or legs), discoid lupus erythematosus (red, coin-shaped scales or crusts on the scalp, cheeks, and ears), and eczema (red and itchy skin). Autoimmune skin disorders are conditions in which immune cells attack the body's healthy cells, causing inflammation. Topinate Gel 30 gm can suppress the immune system and reduce inflammation.
Topinate Gel 30 gm comprises Clobetasol, an active corticosteroid with anti-inflammatory properties on the skin. It reduces swelling, redness, and itching by inhibiting the production of certain chemical messengers in the body that cause inflammation. Thus, Topinate Gel 30 gm aids in treating skin conditions such as psoriasis, eczema, lichen planus, and discoid lupus erythematosus.
Always use the right amount of Topinate Gel 30 gm as advised by the doctor or pharmacist. It would be best to use Topinate Gel 30 gm regularly to get the maximum benefit. When Topinate Gel 30 gm is applied to the skin, some persons experience a burning or stinging sensation for a few minutes. After a few days of use, this will no longer occur.
Inform your doctor if you are allergic to Clobetasol or any of the other ingredients present in this medicine. Do not use Topinate Gel 30 gm to treat acne, rosacea (facial flushing on and around the nose), perioral dermatitis (red or scaly rashes around the mouth), anogenital pruritis (itching around the anus or genitals), itchy, broken, or infected skin which is not inflamed, and widespread plaque psoriasis (except single lesions).While applying, make sure it does not come in contact with the eye. If Topinate Gel 30 gm accidentally comes in contact with eyes, rinse with warm water thoroughly. Please do not use it on unaffected areas or for other skin infections without informing your doctor.Do not use Topinate Gel 30 gm in childrenunder 12 years of age without a doctor's advice.
Uses of Topinate Gel 30 gm
Autoimmune skin diseases such as psoriasis, eczema, lichen planus, and discoid lupus erythematosus
Medicinal Benefits
The skin gets inflamed when chemical mediators release chemicals into the skin that cause inflammation. It leads to rashes, swelling, and itching, which can be treated by Topinate Gel 30 gm. It targets the immune system and lowers the immune response, providing some time for the inflamed skin to heal.
Directions for Use
Cream/Ointment: It is only for external use. Take a small amount of it on the fingertip and apply it as a thin layer on the clean and dry affected area as prescribed by your doctor. Avoid contact of this product with your nose or eyes. In case of accidental contact with these areas, rinse with water thoroughly. Wash your hands before and after using if your hands are not affected to prevent the spread of infection.Shampoo: It can be used in place of regular shampoo during bathing or as directed by a healthcare professional.
Storage
Store in a cool and dry place away from sunlight
Side Effects of Topinate Gel 30 gm
- Burning or stinging sensation
- Pain (application site)
- Irritation or itching
- Skin thinning may cause stretch marks
- Blood vessels under the surface of your skin may become more noticeable.
In-Depth Precautions and Warning
Drug Warnings
Inform your doctor before using Topinate Gel 30 gm, if you have previously had an allergic reaction (hypersensitivity) with another steroid. If there is an overdose, clean the area thoroughly and re-apply the medicine. Apply the medicationcarefully if you are using it on eyelids or near the eyes, as there is a risk of cataracts or glaucoma if the drug enters the eye frequently. Topinate Gel 30 gm can enter the skin easily and may cause skin thinning because of repeated application. So, apply it carefully when using on broken or damaged skin and large surface area of skin. Inform your doctor immediately if you experience vision problems or any other abnormal signs.Do not use Topinate Gel 30 gm at the same time as other creams or ointments such as a moisturiser. Wait at least 30 minutes between using clobetasol and any other product.
Drug Interactions
Drug-drug interactions:Topinate Gel 30 gm may interact withHIV medication (ritonavir) and antifungal medication(itraconazole).
Drug-food interactions:No interactions found.
Drug-disease interactions:Topinate Gel 30 gm should be used with caution in patients with diabetes, eye problems, skin infections, and adrenal gland problems.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
safe if prescribed
Topinate Gel 30 gm may not interact with alcohol.
Pregnancy
caution
Pregnant women should consult a doctor before using Topinate Gel 30 gm.
Breast Feeding
caution
Topinate Gel 30 gm should be used with caution in breastfeeding mothers. However, if prescribed by your doctor and Topinate Gel 30 gm is applied on the chest, make sure the affected area does not come into contact with the baby's mouth while breastfeeding.
Driving
safe if prescribed
Topinate Gel 30 gm does not show any effect on driving. But contact a doctor if you get any problems with your vision. Do not drive if you have problems with your eyesight after using Topinate Gel 30 gm.
Liver
caution
Topinate Gel 30 gm should be used with caution in patients with liver diseases.
Kidney
caution
Topinate Gel 30 gm should be used in patients with kidney diseases only when prescribed by a doctor.
Children
caution
Topinate Gel 30 gm should not be used in children under 12 years of age without a doctor's advice.
Habit Forming
No
Diet & Lifestyle Advise
- Eat foods rich in quercetin (a flavonoid) such as apples, cherry, broccoli, spinach and blueberries.
- Consuming food rich in probiotics helps in developing the immune system against allergies.
- Limit intake of food that might trigger allergies such as dairy products, soy, eggs, and nuts.
- Avoid consumption of foods with excess sugar as it may flare-up inflammation.
- Include fruits, vegetables, whole grains, healthy fats and fish in your diet.
- Avoiding getting in contact with harsh soaps, detergents and rough fabrics.
FAQs
What is the side effects of topinate Cream? ›
The most common side effects of using TOPINATE CREAM are thinning of the skin, widening of small veins in the skin, skin discomfort and dryness. Contact your doctor if any of your symptoms get worse or persist.
What is topinate gel used for? ›Topinate Gel is a Gel manufactured by SYSTOPIC LABS. It is commonly used for the diagnosis or treatment of redness, psoriasis, itching, dryness and swelling of skin , dryness and swelling of scalp, itching, redness.
Is Topinate a steroid? ›Topinate Cream is a steroid. It works by blocking the production of certain chemical messengers that make the skin red, swollen and itchy.
How do you use topinate solution for hair? ›DIRECTIONS FOR USE
It is for external use only. Wash your hands before and after application. Apply a thin layer of TOPINATE SOLUTION on the affected area. Do not cover the affected site after applying TOPINATE SOLUTION.
High doses or long-term use of clobetasol topical can lead to thinning skin, easy bruising, changes in body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.
Do creams have side effects? ›These reactions may include burning, crusting, dryness, flaking, itching, oozing, pain, redness, sores or ulcers, or swelling. Scarring or permanent pigment change from the cream is very unusual.
Is clobetasol safe to use everyday? ›Do not use clobetasol for more than 4 weeks without talking to a doctor. If you need treatment for a long time, a doctor may recommend that you use a milder cream or ointment.
What happens when you stop using clobetasol? ›If you stop taking the drug suddenly or don't take it at all: Your skin problems may not improve. If you miss doses or don't take the drug on schedule: Your medication may not work as well or may stop working completely. If you take too much: Clobetasol could reach your blood, which can cause problems.
Is clobetasol a strong steroid? ›Clobetasol (including scalp treatment and shampoo) is a very strong steroid. If you have applied clobetasol to your skin, wait at least 30 minutes before using another product, like a moisturiser.
Who should not use clobetasol? ›Acne vulgaris (skin problem) or. Perioral dermatitis (skin problem) or. Rosacea (skin problem)—Should not be used in patients with these conditions.
Does clobetasol cause weight gain? ›
Weight gain is not a common side effect of clobetasol. Sudden weight gain when using clobetasol can be a sign of a serious problem and requires immediate medical attention. Similarly, changes in the way body fat is distributed can be another sign of a serious side effect.
Does clobetasol have side effects? ›Talk to your doctor right away if you or your child have more than one of these symptoms while you are using this medicine: blurred vision, dizziness or fainting, a fast, irregular, or pounding heartbeat, increased thirst or urination, irritability, or unusual tiredness or weakness.
Can I leave clobetasol on my scalp? ›If you are using clobetasol propionate shampoo, use it as you normally would use a shampoo but leave it on your scalp for 15 minutes before rinsing out. Avoid contact with the lips and eyes.
How long does clobetasol stay in your system? ›by Drugs.com
Some researchers have found that suppression of cortisol levels is still apparent 96 hours after topical use of this medicine, which implies that clobetasol can stay in your system for long periods of time, possibly for up to a few weeks.
You may wash your hair as usual after applying and rinsing off clobetasol shampoo. Clobetasol foam may catch fire. Stay away from open fire, flames, and do not smoke while you are applying clobetasol foam, and for a short time afterward. This medication is only for use on the skin.
Can clobetasol get into your bloodstream? ›Using clobetasol continuously for a long time can mean some of the medicine gets into your bloodstream. If this happens, there's a very small chance it can cause serious side effects. Using clobetasol for a long time can make your skin thinner or cause stretch marks.
Does clobetasol affect blood pressure? ›Some of the serious side effects of Clobetasol are
Low blood pressure. Fainting. Dizziness.
sleep problems (insomnia), weight gain, puffiness in your face, muscle weakness, or.
Does topical cream get into your bloodstream? ›Creams, gels and sprays can apply a treatment directly to an area of wounded skin and are called topical or local treatments. They don't really pass into our bloodstream so don't affect any other parts of the body.
How long does it take for clobetasol to absorb? ›It takes about one to three days for clobetasol propionate to start working when it is being used to treat eczema.
Do topical steroids get into bloodstream? ›
If potent or very potent topical corticosteroids are used for a long time or over a large area, there's a risk of the medicine being absorbed into the bloodstream and causing internal side effects, such as: decreased growth in children.
What are the warnings for clobetasol? ›Check with your doctor right away if you or your child have a skin rash, burning, stinging, swelling, or irritation on the skin. Make sure your doctor knows that you are using clobetasol cream, gel, or spray. You may need to stop using this medicine several days before having surgery.
Can I stop using clobetasol suddenly? ›Topical corticosteroids can help treat chronic inflammation, but stopping them can lead to adverse effects, such as burning, itching, or peeling of the skin. For adults, withdrawal symptoms often occur after using a topical corticosteroid for 12 months then stopping.
What is the success rate of clobetasol? ›In a systematic review of the literature with 7 studies and 249 participants, clobetasol achieved improvement rates and remission rates of 70% to 89% and 20% to 35%, respectively.
Why was clobetasol taken off the market? ›Taro Pharmaceuticals has issued a voluntary recall of 1 lot of Clobetasol Propionate Ointment USP, 0.05%, 60g tubes to the consumer level due to the presence of Ralstonia pickettii (R. pickettii) bacteria discovered by the manufacturer through routine testing.
Can clobetasol cause hair loss? ›Hair loss or hair thinning may also occur, but this is a very rare side effect and is estimated to occur in only 1 out of every 300 people who use clobetasol. Clobetasol is a potent topical steroid and is not a good option for hair and scalp conditions that are not associated with inflammation.
How many times can I apply clobetasol? ›Adults—Apply to the affected area of the scalp 2 times per day, once in the morning and once at night. Children 12 to 17 years of age—Apply to the affected area of the scalp 2 times per day, once in the morning and once at night. Children younger than 12 years of age—Use is not recommended.
Is clobetasol stronger than prednisone? ›Results: Data derived from the existing literature demonstrated that hydrocortisone 2.5% ointment, triamcinolone 0.1% ointment, and clobetasol 0.05% foam achieved effective skin concentrations greater than the effective concentration achieved by oral prednisone.
Does skin recover after steroid cream? ›It is not unusual for skin conditions to flare up or return shortly after stopping topical corticosteroids. However, very infrequently, a severe type of topical steroid withdrawal reaction can occur, which may also be known as red skin syndrome or topical steroid addiction.
What drugs interact with clobetasol? ›Clobetasol has no known severe interactions with other drugs. Clobetasol has no known serious interactions with other drugs.
Is clobetasol hazardous? ›
Hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation (lung irritant). Slightly hazardous in case of skin contact (permeator). Potential Chronic Health Effects: Slightly hazardous in case of skin contact (sensitizer).
What are the health benefits of clobetasol? ›CLOBETASOL (kloe BAY ta sol) reduces swelling, redness, itching, or rashes caused by skin conditions, such as eczema and psoriasis. It works by decreasing inflammation of the skin. It belongs to a group of medications called topical steroids.
Can I use regular shampoo after clobetasol? ›Lather and rinse your hair and scalp completely. Rinse any other parts of your body that come into contact with clobetasol propionate shampoo, such as your hands, face, neck and shoulders. No other shampoo is needed, but you may wash your hair with a non-medicated shampoo after using clobetasol propionate shampoo.
Do you have to wean off clobetasol? ›You can stop whenever you prefer. It is ultimately up to you how soon you stop. Gradually cutting down on the strength of the TS creams is my recommendation based on research papers on the deterious effects of going cold turkey.
Does hair grow back after clobetasol? ›Clobetasol is effective at stimulating hair growth. Research has shown hair regrowth was stimulated in about 20 to 25% of people who used clobetasol ointment and in about 47% of people who used clobetasol foam. Regrowth was noticed as early as six weeks into treatment but may take up to 12 to 14 weeks to develop.
What happens if you use clobetasol more than 2 weeks? ›Using more cream or ointment than recommended, or applying clobetasol propionate for longer than two weeks for eczema or psoriasis, could lead to side effects such as skin thinning, and rarely, growth retardation in children, cataracts, glaucoma, or suppression of the hypothalamic-pituitary-adrenal axis.
Can clobetasol cause mood swings? ›Ever since he commenced clobetasol cream, he began to experience severe mood swings. He described these experiences to immediately follow the application of the cream to his body and the episodes lasted upto couple of hours each time.
How long does topical clobetasol stay in your system? ›Some researchers have found that suppression of cortisol levels is still apparent 96 hours after topical use of this medicine, which implies that clobetasol can stay in your system for long periods of time, possibly for up to a few weeks. Clobetasol is not recommended to be used for more than two consecutive weeks.
Can you use clobetasol indefinitely? ›Do not keep applying clobetasol propionate for long periods continuously without the advice of your doctor.
How many times a day can you apply clobetasol? ›Adults—Apply to the affected area of the scalp 2 times per day, once in the morning and once at night. Children 12 to 17 years of age—Apply to the affected area of the scalp 2 times per day, once in the morning and once at night.