Bisquick Chicken Enchilada Casserole (2024)

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ByBrandie

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Bisquick Chicken Enchilada Bake is an easy, family-friendly casserole made with rotisserie chicken, taco seasoning, enchilada sauce and mozzarella cheese!

A SHORTCUT CHICKEN CASSEROLE RECIPE

Like most casseroles, this one may not be pretty but it is absolutely delicious. It only needs a handful of ingredients. It has incredible flavor thanks to the taco seasoning and green chile enchilada sauce. It’s not crazy spicy and my whole family loved it!

Bisquick Chicken Enchilada Casserole (1)

FREQUENTLY ASKED QUESTIONS (FAQ’S)

What is the best chicken to use for this casserole?

Use store-bought rotisserie chicken and dice it up. It cuts down on prep time. Or if you have any leftover cooked chicken, you can use that as well. You could also bake or boil a couple of chicken breasts to use in this recipe.

What toppings would you suggest?

Have fun with toppings like sour cream, sliced olives, shredded lettuce and diced tomatoes! Pretty much anything you would put on a taco, you can put on here.

What could I use besides Bisquick?

You should be able to use any pre-made biscuit mix here, even the heart healthy one. If you want, you can easily make your own Homemade Bisquick!

Could I add beans to the casserole?

Absolutely! You could add some pinto beans or black beans.

What should I serve with Chicken Enchilada Bake

My personal preference would be a salad or some sort of steamed vegetable like broccoli. If you are okay with more carbs then I would try some restaurant style rice! Some homemade Slow Cooker Refried Beans would be delicious too!

How do I store leftovers?

Leftovers can be stored in an airtight container in the refrigerator for up to 3 days. This can also be frozen. Place in a freezer safe container where it will last up to 3 months. Just make sure to wrap it well to protect against freezer burn.

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INGREDIENTS NEEDED: (SEE RECIPE CARD BELOW FOR THE FULL RECIPE)

  • Bisquick mix– use the store bought mix, or you can make your own homemade Bisquick mix or use any other brand of biscuit mix.
  • mild green chile enchilada sauce– you could swap this out for red enchilada sauce if you prefer.
  • cream of chicken soup– use a canned version, or make your own homemade cream of chicken soup.
  • taco seasoning– make your own taco seasoning with this homemade taco seasoning recipe, or grab a premade packet.
  • diced cooked chicken – I find this easiest with a store bought rotisserie chicken. It makes for quick work but you honestly could even use canned chicken (2-10 ounce cans, drained) or you could boil or bake some chicken.
  • shredded Monterey jack cheese– you can use the stuff from the bag, or grab a block and shred it fresh from the block. You could also swap this out for cheddar cheese, mozzarella cheese, or pepper jack cheese if you like more of a kick or any other shredded cheese that you enjoy that will melt easily.
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HOW TO MAKE BISQUICK CHICKEN ENCHILADA BAKE:

Preheat oven to 375F degrees.Spray a 9×13-inch baking dish with nonstick cooking spray.In a medium bowl, combine Bisquick mix with water. Stir well (batter will be lumpy.) Pour into baking dish and spread out evenly.

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Using the same bowl (so as not to make any more dirty dishes than is necessary), combine enchilada sauce, cream of chicken soup, diced chicken, taco seasoning and 1 cup shredded cheese. Combine well then evenly spread over the Bisquick layer.

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Top with remaining shredded cheese. Bake uncovered for 30 minutes, until bubbly and golden around the edges.

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Allow to cool for several minutes, then slice and serve. Top with shredded lettuce, diced tomatoes and sour cream.

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CRAVING MORE RECIPES?

  • Cornbread Taco Bake
  • White Chicken Enchiladas
  • Bisquick Coffee Cake
  • Bisquick Taco Casserole
  • Bisquick Burrito Bake
  • Biscuit Blueberry Cake with Bisquick
  • Taco Bubble Up
  • Mexican Lasagna
  • Crock Pot Refried Beans
  • Copycat Taco Bell Mexican Pizza
  • White Chicken Enchiladas (For Two)

Originally posted: September 2014
Updated photos & republished: April 2024

Bisquick Chicken Enchilada Casserole (8)

Bisquick Chicken Enchilada Bake

Bisquick Chicken Enchilada Bake is a delicious casserole made with rotisserie chicken, taco seasoning, enchilada sauce and mozzarella cheese.

4.91 from 21 votes

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Prep Time: 10 minutes minutes

Cook Time: 30 minutes minutes

Total Time: 40 minutes minutes

Servings: 6 servings

Author: Brandie @ The Country Cook

Ingredients

For topping:

Instructions

  • Preheat oven to 375F degrees. Spray a 9×13-inch baking dish with nonstick cooking spray.

  • In a medium bowl, combine 2 cups Original Bisquick mix with 1 cup water. Stir well (batter will be lumpy.)

    Bisquick Chicken Enchilada Casserole (9)

  • Pour into baking dish and spread out evenly.

    Bisquick Chicken Enchilada Casserole (10)

  • Using the same bowl (so as not to make any more dirty dishes than is necessary), combine 10 ounce can mild green chile enchilada sauce, 10.75 ounce can cream of chicken soup, 2 Tablespoons taco seasoning, 2 cups diced, cooked chicken and 1 cup shredded monterey jack cheese.

    Bisquick Chicken Enchilada Casserole (11)

  • Combine well then evenly spread over the Bisquick layer.

    Bisquick Chicken Enchilada Casserole (12)

  • Top with remaining 1 cup shredded monterey jack cheese.

    Bisquick Chicken Enchilada Casserole (13)

  • Bake uncovered for 30 minutes, until bubbly and golden around the edges. Top with a little dried parsley (optional) (or chopped cilantro) and serve!

    Bisquick Chicken Enchilada Casserole (14)

Notes

  • Please refer to my FAQ’s (Frequently Asked Questions) and ingredient list above for other substitutions or for the answers to the most common questions.

Course: Main Course

Cuisine: American

Nutrition

Calories: 399kcal | Carbohydrates: 30g | Protein: 20g | Fat: 21g | Sodium: 1639mg | Fiber: 1g | Sugar: 5g

Nutritional Disclaimer

“The Country Cook” is not a dietician or nutritionist, and any nutritional information shared is an estimate. If calorie count and other nutritional values are important to you, we recommend running the ingredients through whichever online nutritional calculator you prefer. Calories and other nutritional values can vary quite a bit depending on which brands were used.

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Leave a Reply

  1. Bisquick Chicken Enchilada Casserole (19)
    I’m on a roll with your recipes, Brandie! You make it easy for this single Dad to cook on a budget. I made this chicken enchilada bake recipe tonight for my daughter. It was delicious, quick and simple! I used red enchilada sauce and a mix of monterey jack and pepper jack cheeses to add a little more spice to the dish. I also added chopped cilantro instead of parsley. We have plenty of leftovers. Thank you!

    Reply

    1. I always love hearing when the kids love a recipe! Thanks so much Jay!

      Reply

  2. Bisquick Chicken Enchilada Casserole (20)
    Excellent recipe… made exactly as written. Next time I will try ground beef.

    Reply

  3. Will this work with gluten free bisquick?

    Reply

  4. Can you use red enchilada sauce. I don’t have green

    Reply

  5. Mozzarella cheese is not listed in the ingredient list but it is listed at the top of the recipe. I am assuming you can use shredded taco seasoned cheese, monterey jack cheese, etc.. It sounds amazing. I cannot wait to try it.

    Reply

    1. Hi Sherri, you can absolutely use your favorite cheese in this. As long as it is a good melting cheese – it will work! Hope you love it!

      Reply

  6. Suggestions on cutting down the recipe for two people? I am only one person and don’t cook that much but am game to try this since I love chicken enchiladas. Also, could you just put the mix in store bought tortilla shells or soft taco shells?

    Reply

  7. Love this recipe and when my granddaughter came over and tasted it she said “Awesome, it will better if you added some black beans and mexi corn.” She was right. My next batch was great.

    Reply

  8. Bisquick Chicken Enchilada Casserole (21)
    Thannks, Brandie! I’ve made your recipe and we think it’s a winner! Keeping this in my recipe rotation. You’ve got my creative juices flowing. Think I’ll try the same recipe with a cornbread base using ground beef next time just to change it up. I’m a fan of Rotel tomatoes with green chilies so might add that for part of the soup to give it some punch. Such a versatile recipe!

    Reply

  9. Bisquick Chicken Enchilada Casserole (22)
    I made the Bisquick enchalada chicken bake for dinner tonight. Because my husband does not like chicken, I made a couple adjustments. Used ground beef lean in place of chicken, crm of mshrm soup instead of crm of chicken soup. It was OUTSTANDING!!! I and my hubby loved it. Great recipe!! Thanks for sharing.

    Reply

    1. I love the changes you made Susan! Thanks so much for coming back to let me know!

      Reply

  10. I’m going to try this. Don’t we ALL have Bisquick in our pantry??

    But, what about mixing some cornmeal into the Bisquick layer? Wonder what the proportions would be.

    Reply

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